PANCE Study Guide

215 High-Yield Concepts for the PANCE (2025+ NCCPA Format)

A focused, high-yield concept review for the Physician Assistant National Certifying Exam (PANCE) — 215 concepts in 8 parts mirroring the official NCCPA content blueprint (effective January 2025), each with key facts, a strategy tip, and a worked example: Part 1 — PANCE Exam Essentials & Blueprint. Part 2 — Cardiovascular (11%) + Pulmonary (9%) systems. Part 3 — GI/Nutrition (8%) + Musculoskeletal (8%) + Dermatologic (4%). Part 4 — Infectious Diseases (7%) + Hematologic (5%). Part 5 — Neurologic (7%) + Psychiatry & Behavioral Science (7%). Part 6 — Endocrine (6%) + Renal (5%) + Genitourinary (4%). Part 7 — EENT (6%) + Reproductive (7%). Part 8 — Professional Practice (6%) + Task-Category Strategy. Includes verified format facts sourced from nccpa.net on 2026-09-19: the new 2025+ format of five blocks of 60 questions with 60 minutes per block (300 questions / 300 minutes of testing, plus 45 minutes of breaks and a 15-minute tutorial), a scaled score range of 200–800 with a passing standard of 350, the official 14-category content blueprint (94%) plus Professional Practice (6%), the eight task categories (Diagnosis 18%, History & Physical Exam 16%, Clinical Intervention 16%, Pharmacology 15%, Health Maintenance & Education 11%, Diagnostics & Lab Studies 10%, Foundational Science 8%, Professional Practice 6%), surgical topics at 8–10% and pediatric topics at 12–15% of questions, year-round administration at 300+ Pearson VUE centers, the $550 application fee, and the ARC-PA eligibility and six-years-six-attempts rule. Independent companion — not affiliated with, endorsed by, or sponsored by NCCPA; confirm current exam details, fees, and eligibility at nccpa.net before applying.